Modelling and optimal control analysis of Lassa fever disease
نویسندگان
چکیده
منابع مشابه
Lassa fever and Marburg virus disease.
In the light of progress in virology, it comes as a surprise to discover a disease, an epidemic disease moreover, caused by a "new "virus. This has happened twice in recent years. The diseases, Marburg virus disease and Lassa fever, are caused by unrelated viruses that are highly pathogenic for man and both have been responsible for illness and death among laboratory scientists and medical pers...
متن کاملPathogenesis of Lassa Fever
Lassa virus, an Old World arenavirus (family Arenaviridae), is the etiological agent of Lassa fever, a severe human disease that is reported in more than 100,000 patients annually in the endemic regions of West Africa with mortality rates for hospitalized patients varying between 5-10%. Currently, there are no approved vaccines against Lassa fever for use in humans. Here, we review the publishe...
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We propose and analyze a compartmental nonlinear deterministic mathematical model for the typhoid fever outbreak and optimal control strategies in a community with varying population. The model is studied qualitatively using stability theory of differential equations and the basic reproductive number that represents the epidemic indicator is obtained from the largest eigenvalue of the next-gene...
متن کاملLassa fever: the challenges of curtailing a deadly disease
Today Lassa fever is mainly a disease of the developing world, however several imported cases have been reported in different parts of the world and there are growing concerns of the potentials of Lassa fever Virus as a biological weapon. Yet no tangible solution to this problem has been developed nearly half a decade after its identification. Hence, the paper is aimed at appraising the problem...
متن کاملLassa Fever, Nigeria, 2005–2008
To the Editor: Lassa fever affects ≈100,000 persons per year in West Af-rica (1). The disease is caused by Las-sa virus, an arenavirus, and is associated with bleeding and organ failure. The case-fatality rate in hospitalized patients is 10%–20%. The reservoir of the virus is multimammate mice (Mastomys natalensis). Investigations in the 1970s and 1980s pointed to the existence of 3 disease-end...
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ژورنال
عنوان ژورنال: Informatics in Medicine Unlocked
سال: 2020
ISSN: 2352-9148
DOI: 10.1016/j.imu.2020.100419